Jih-Hwa Guh Selected Research

Leukemia

4/2020	Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
1/2019	Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1β Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation.
1/2019	Dihydroartemisinin-Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity.
12/2013	Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades.
6/2013	Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy.
1/2005	Denbinobin-mediated anticancer effect in human K562 leukemia cells: role in tubulin polymerization and Bcr-Abl activity.
6/2004	Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway.
5/2004	Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes.

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Jih-Hwa Guh Research Topics

Disease

57	Neoplasms (Cancer) 04/2024 - 02/2003
55	Prostatic Neoplasms (Prostate Cancer) 02/2024 - 09/2002
19	Hepatocellular Carcinoma (Hepatoma) 03/2023 - 03/2004
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 07/2003
8	Leukemia 04/2020 - 05/2004
7	Breast Neoplasms (Breast Cancer) 01/2022 - 06/2004
6	Inflammation (Inflammations) 12/2020 - 07/2002
5	Lung Neoplasms (Lung Cancer) 04/2024 - 06/2010
5	Colorectal Neoplasms (Colorectal Cancer) 12/2008 - 12/2006
4	Ovarian Neoplasms (Ovarian Cancer) 03/2024 - 01/2015
4	Mitochondrial Diseases (Mitochondrial Disease) 12/2023 - 01/2005
3	Hyperplasia 06/2011 - 06/2003
2	Triple Negative Breast Neoplasms 01/2019 - 11/2011
2	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2018 - 09/2013
2	Cardiotoxicity 01/2018 - 02/2008
2	Glioblastoma (Glioblastoma Multiforme) 09/2015 - 05/2014
2	Neoplasm Metastasis (Metastasis) 03/2015 - 11/2007
2	Hypoxia (Hypoxemia) 11/2011 - 09/2009
2	Vascular System Injuries 12/2008 - 06/2003
2	Acute Promyelocytic Leukemia 10/2005 - 01/2005
1	Aneuploidy (Aneuploid) 03/2024
1	Squamous Cell Carcinoma of Head and Neck 03/2024

Drug/Important Bio-Agent (IBA)

32	Hormones (Hormone)IBA 02/2024 - 02/2004
12	TubulinIBA 01/2020 - 09/2002
8	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 10/2007
7	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2005
7	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 10/2007
6	Paclitaxel (Taxol)FDA LinkGeneric 03/2024 - 09/2002
6	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2014 - 12/2006
6	AndrogensIBA 05/2011 - 09/2002
5	Adenosine Triphosphatases (ATPase)IBA 03/2024 - 12/2013
4	Matrix Metalloproteinases (MMPs)IBA 04/2024 - 01/2006
4	CaspasesIBA 12/2023 - 02/2008
4	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 06/2020 - 09/2009
4	Cardiac GlycosidesIBA 01/2020 - 09/2002
4	NF-kappa B (NF-kB)IBA 08/2010 - 10/2005
4	evodiamineIBA 09/2009 - 05/2004
3	Doxazosin (Cardura)FDA LinkGeneric 04/2024 - 10/2007
3	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 01/2022
3	GlycosidesIBA 03/2024 - 01/2014
3	CardenolidesIBA 03/2024 - 01/2014
3	Cisplatin (Platino)FDA LinkGeneric 02/2024 - 01/2015
3	artenimol (dihydroartemisinin)IBA 03/2023 - 01/2019
3	Bile Acids and Salts (Bile Acids)IBA 03/2023 - 01/2019
3	TriazolesIBA 03/2023 - 11/2016
3	LipidsIBA 10/2021 - 06/2010
3	Phosphotransferases (Kinase)IBA 10/2021 - 12/2011
3	MK 2206IBA 01/2019 - 01/2015
3	CytokinesIBA 01/2019 - 05/2005
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 05/2005
3	Peptides (Polypeptides)IBA 11/2017 - 02/2015
3	Ouabain (G Strophanthin)IBA 09/2015 - 09/2002
3	Type I DNA Topoisomerases (Topoisomerase I)IBA 11/2014 - 07/2012
3	CamptothecinIBA 07/2012 - 09/2009
3	Terazosin (Hytrin)FDA LinkGeneric 06/2011 - 02/2003
3	lissamine rhodamine B (sulforhodamine B)IBA 05/2011 - 10/2005
3	bromovulone IIIIBA 08/2006 - 04/2004
3	ProstaglandinsIBA 08/2006 - 01/2005
3	IndazolesIBA 01/2006 - 03/2005
2	Type II DNA Topoisomerases (Topoisomerase II)IBA 12/2023 - 02/2008
2	EstersIBA 03/2023 - 05/2011
2	WZB117IBA 11/2022 - 01/2019
2	CholesterolIBA 10/2021 - 01/2018
2	4-toluenesulfonamideIBA 10/2021 - 01/2018
2	Phosphodiesterase 5 InhibitorsIBA 01/2020 - 01/2018
2	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 09/2002
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2020 - 01/2018
2	SaponinsIBA 01/2018 - 02/2014
2	Histone Deacetylase InhibitorsIBA 01/2018 - 09/2013
2	Topoisomerase II InhibitorsIBA 01/2018 - 02/2008
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 09/2015 - 08/2012
2	reevesioside FIBA 09/2015 - 12/2013
2	AnthraquinonesIBA 11/2014 - 02/2008
2	Histone Deacetylases (Histone Deacetylase)IBA 08/2014 - 09/2013
2	Glutathione (Reduced Glutathione)IBA 05/2014 - 05/2014
2	SurvivinIBA 04/2014 - 01/2013
2	TriterpenesIBA 02/2014 - 01/2006
2	antroquinonolIBA 08/2012 - 01/2010
2	Protein Kinases (Protein Kinase)IBA 11/2011 - 07/2008
2	Transcription Factors (Transcription Factor)IBA 11/2011 - 03/2007
2	Prazosin (Minipress)FDA LinkGeneric 06/2011 - 10/2007
2	Endoplasmic Reticulum Chaperone BiPIBA 05/2011 - 11/2009
2	Cyclooxygenase InhibitorsIBA 08/2010 - 07/2002
2	dendrophenolIBA 06/2010 - 07/2008
2	Plant ExtractsIBA 11/2009 - 01/2006
2	Etoposide (VP 16)FDA LinkGeneric 11/2009 - 02/2008
2	TunicamycinIBA 11/2009 - 04/2008
2	denbinobinIBA 11/2008 - 01/2005
2	2-phenyl-4-oxohydroquinolineIBA 02/2008 - 06/2007
2	GenisteinIBA 03/2007 - 06/2004
2	cyclopentenoneIBA 08/2006 - 01/2005
2	AlkaloidsIBA 01/2005 - 05/2004
1	cadherin 5IBA 04/2024
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2024
1	dapagliflozinIBA 03/2024
1	CanagliflozinIBA 03/2024

Therapy/Procedure

14	Therapeutics 03/2024 - 09/2002
11	Drug Therapy (Chemotherapy) 10/2021 - 01/2005
9	Castration 02/2024 - 09/2015
2	Oral Administration 11/2011 - 10/2007